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Inhibition of Period Gene Expression Causes Repression of Cell Cycle Progression and Cell Growth in the Bombyx mori Cells
Circadian clock system disorders can lead to uncontrolled cell proliferation, but the molecular mechanism remains unknown. We used a Bombyx mori animal model of single Period gene (BmPer) expression to investigate this mechanism. A slow growing developmental cell model (Per-KD) was isolated from a B...
Autores principales: | Qiu, Jian-Feng, Li, Xue, Cui, Wen-Zhao, Liu, Xiao-Fei, Tao, Hui, Yang, Kun, Dai, Tai-Ming, Sima, Yang-Hu, Xu, Shi-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509393/ https://www.ncbi.nlm.nih.gov/pubmed/31130878 http://dx.doi.org/10.3389/fphys.2019.00537 |
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