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A bell‐shaped pattern of urinary aquaporin‐2‐bearing extracellular vesicle release in an experimental model of nephronophthisis

The DBA/2‐FG pcy (pcy) mouse is a model of human nephronophthisis, a recessive cystic kidney disease. Renal expression of aquaporin‐2 (AQP2), a water channel protein, has been shown to be altered in pcy mice. However, the relationship between the renal expression and its release in urinary extracell...

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Detalles Bibliográficos
Autores principales: Mikoda, Nobuyuki, Sonoda, Hiroko, Oshikawa, Sayaka, Hoshino, Yuya, Matsuzaki, Toshiyuki, Ikeda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509436/
https://www.ncbi.nlm.nih.gov/pubmed/31074077
http://dx.doi.org/10.14814/phy2.14092