DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells

Type I collagen is the major adhesive component in breast interstitial stroma, which represents the first barrier against tumor cell invasion after basement-membrane degradation. Among cellular receptors, type I collagen is able to activate discoidin domain receptors DDR1 and DDR2. We have previousl...

Descripción completa

Detalles Bibliográficos
Autores principales: Saby, Charles, Collin, Guillaume, Sinane, Maha, Buache, Emilie, Van Gulick, Laurence, Saltel, Frédéric, Maquoi, Erik, Morjani, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509437/
https://www.ncbi.nlm.nih.gov/pubmed/31130862
http://dx.doi.org/10.3389/fphar.2019.00462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509437/
https://www.ncbi.nlm.nih.gov/pubmed/31130862
http://dx.doi.org/10.3389/fphar.2019.00462

Ejemplares similares