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“Balancing” balancing selection? Assortative mating at the major histocompatibility complex despite molecular signatures of balancing selection

In vertebrate animals, genes of the major histocompatibility complex (MHC) determine the set of pathogens to which an individual's adaptive immune system can respond. MHC genes are extraordinarily polymorphic, often showing elevated nonsynonymous relative to synonymous sequence variation and sh...

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Detalles Bibliográficos
Autores principales: Slade, Joel W. G., Watson, Matthew J., MacDougall‐Shackleton, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509439/
https://www.ncbi.nlm.nih.gov/pubmed/31110668
http://dx.doi.org/10.1002/ece3.5087