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Stimulation of constitutive nitric oxide uniquely and compensatorily regulates intestinal epithelial cell brush border membrane Na absorption

In the mammalian small intestine, sodium is primarily absorbed by Na(+)/H(+) exchange (NHE3) and Na‐glucose cotransport (SGLT1) in the brush border membrane (BBM) of villus cells. However, how enhanced cellular constitutive nitric oxide (cNO) may affect NHE3 and SGLT1 remains unclear. Both in vivo i...

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Detalles Bibliográficos
Autores principales: Palaniappan, Balasubramanian, Manoharan, Palanikumar, Arthur, Subha, Singh, Soudamani, Murughiyan, Usha, Sundaram, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509550/
https://www.ncbi.nlm.nih.gov/pubmed/31074207
http://dx.doi.org/10.14814/phy2.14086