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Parenteral Vaccination With a Tuberculosis Subunit Vaccine in Presence of Retinoic Acid Provides Early but Transient Protection to M. Tuberculosis Infection

Most microbes invading through mucosal surfaces cause disease and therefore strategies to induce mucosal immune responses are strongly needed. Vitamin A metabolites, such as retinoic acid (RA), play crucial roles in programming T and B cells to home to mucosal compartments, therefore we evaluated th...

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Detalles Bibliográficos
Autores principales: Riccomi, Antonella, Piccaro, Giovanni, Christensen, Dennis, Palma, Carla, Andersen, Peter, Vendetti, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509564/
https://www.ncbi.nlm.nih.gov/pubmed/31130946
http://dx.doi.org/10.3389/fimmu.2019.00934