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Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have Novel and Unexpectedly Abundant CRISPR-Cas Systems

The Candidate Phyla Radiation (CPR) comprises a huge group of bacteria that have small genomes that rarely encode CRISPR-Cas systems for phage defense. Consequently, questions remain about their mechanisms of phage resistance and the nature of phage that infect them. The compact CRISPR-CasY system (...

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Detalles Bibliográficos
Autores principales: Chen, Lin-Xing, Al-Shayeb, Basem, Méheust, Raphaël, Li, Wen-Jun, Doudna, Jennifer A., Banfield, Jillian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509639/
https://www.ncbi.nlm.nih.gov/pubmed/31130929
http://dx.doi.org/10.3389/fmicb.2019.00928