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Super-resolution Imaging of Structure, Molecular Composition, and Stability of Single Oligonucleotide Polyplexes

[Image: see text] The successful application of gene therapy relies on the development of safe and efficient delivery vectors. Cationic polymers such as cell-penetrating peptides (CPPs) can condense genetic material into nanoscale particles, called polyplexes, and induce cellular uptake. With respec...

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Detalles Bibliográficos
Autores principales: Feiner-Gracia, Natalia, Olea, R. Alis, Fitzner, Robert, El Boujnouni, Najoua, van Asbeck, Alexander H., Brock, Roland, Albertazzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509642/
https://www.ncbi.nlm.nih.gov/pubmed/31001985
http://dx.doi.org/10.1021/acs.nanolett.8b04407