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Quantification of microRNA in plasma using probe based TaqMan assays: is microRNA purification required?

OBJECTIVE: Circulating microRNAs are promising diagnostics and prognostics biomarkers in a wide variety of diseases. However, there is a critical reproducibility challenge, which in part may be due to preanalytical factors. MicroRNA purification has been identified as the major contributor to the to...

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Detalles Bibliográficos
Autores principales: Binderup, Helle Glud, Madsen, Jonna Skov, Brasen, Claus Lohman, Houlind, Kim, Andersen, Rikke Fredslund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509816/
https://www.ncbi.nlm.nih.gov/pubmed/31077242
http://dx.doi.org/10.1186/s13104-019-4301-5