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Age-associated decrease in de novo donor-specific antibodies in renal transplant recipients reflects changing humoral immunity

BACKGROUND: Older age at organ transplantation is associated with increased risk of infection and malignancy but reduced risk of cellular rejection. De novo donor-specific anti-HLA antibodies (dnDSA), are key biomarkers associated with reduced long-term allograft survival, yet there is a lack of dat...

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Detalles Bibliográficos
Autores principales: von Moos, Seraina, Schalk, Gesa, Mueller, Thomas F., Laube, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509825/
https://www.ncbi.nlm.nih.gov/pubmed/31168309
http://dx.doi.org/10.1186/s12979-019-0149-8