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CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics

High-throughput single-cell assays increasingly require special consideration in experimental design, sample multiplexing, batch effect removal, and data interpretation. Here, we describe a lentiviral barcode-based multiplexing approach, CellTag Indexing, which uses predefined genetic barcodes that...

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Detalles Bibliográficos
Autores principales: Guo, Chuner, Kong, Wenjun, Kamimoto, Kenji, Rivera-Gonzalez, Guillermo C., Yang, Xue, Kirita, Yuhei, Morris, Samantha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509836/
https://www.ncbi.nlm.nih.gov/pubmed/31072405
http://dx.doi.org/10.1186/s13059-019-1699-y