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MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC

BACKGROUND: Mediator complex subunit 12 (MED12) is an essential hub for transcriptional regulation, in which mutations and overexpression were reported to be associated with several kinds of malignancies. Nevertheless, the role of MED12 in non-small cell lung cancer (NSCLC) remains to be elucidated....

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Detalles Bibliográficos
Autores principales: Xu, Meng, Wang, Fang, Li, Guibo, Wang, Xiaokun, Fang, Xiaona, Jin, Haoxuan, Chen, Zhen, Zhang, Jianye, Fu, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509838/
https://www.ncbi.nlm.nih.gov/pubmed/31072327
http://dx.doi.org/10.1186/s12943-019-1020-4