Cargando…
MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC
BACKGROUND: Mediator complex subunit 12 (MED12) is an essential hub for transcriptional regulation, in which mutations and overexpression were reported to be associated with several kinds of malignancies. Nevertheless, the role of MED12 in non-small cell lung cancer (NSCLC) remains to be elucidated....
Autores principales: | Xu, Meng, Wang, Fang, Li, Guibo, Wang, Xiaokun, Fang, Xiaona, Jin, Haoxuan, Chen, Zhen, Zhang, Jianye, Fu, Liwu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509838/ https://www.ncbi.nlm.nih.gov/pubmed/31072327 http://dx.doi.org/10.1186/s12943-019-1020-4 |
Ejemplares similares
-
Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization
por: Liu, An, et al.
Publicado: (2016) -
Actin Dynamics, Regulated by RhoA-LIMK-Cofilin Signaling, Mediates Rod Photoreceptor Axonal Retraction After Retinal Injury
por: Wang, Weiwei, et al.
Publicado: (2019) -
The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse
por: Bolger-Munro, Madison, et al.
Publicado: (2021) -
Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G-actin signaling cascade
por: Wang, Xun, et al.
Publicado: (2021) -
Downregulation of LIMK1–ADF/cofilin by DADS inhibits the migration and invasion of colon cancer
por: Su, Jian, et al.
Publicado: (2017)