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Ageing characteristics of bone indicated by transcriptomic and exosomal proteomic analysis of cortical bone cells
BACKGROUND: Degenerative changes in the skeleton play an important role in ageing. As the foremost sensors and orchestrators of bone remodelling, osteocytes contribute significantly to the health of the skeleton. Embedded in a mineralized bone matrix, the osteocyte network and the surrounding lacuna...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509863/ https://www.ncbi.nlm.nih.gov/pubmed/31077243 http://dx.doi.org/10.1186/s13018-019-1163-4 |