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Ageing characteristics of bone indicated by transcriptomic and exosomal proteomic analysis of cortical bone cells

BACKGROUND: Degenerative changes in the skeleton play an important role in ageing. As the foremost sensors and orchestrators of bone remodelling, osteocytes contribute significantly to the health of the skeleton. Embedded in a mineralized bone matrix, the osteocyte network and the surrounding lacuna...

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Detalles Bibliográficos
Autores principales: Zhang, Chenyang, Xu, Shuyu, Zhang, Shufan, Liu, Mengmeng, Du, Haiming, Sun, Ruinan, Jing, Bo, Sun, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509863/
https://www.ncbi.nlm.nih.gov/pubmed/31077243
http://dx.doi.org/10.1186/s13018-019-1163-4