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MD-SVM: a novel SVM-based algorithm for the motif discovery of transcription factor binding sites
BACKGROUND: Transcription factors (TFs) play important roles in the regulation of gene expression. They can activate or block transcription of downstream genes in a manner of binding to specific genomic sequences. Therefore, motif discovery of these binding preference patterns is of central signific...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509868/ https://www.ncbi.nlm.nih.gov/pubmed/31074373 http://dx.doi.org/10.1186/s12859-019-2735-3 |