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Screening drug target combinations in disease-related molecular networks

BACKGROUND: For treating a complex disease such as cancer, some effective means are needed to control biological networks that underlies the disease. The one-target one-drug paradigm has been the dominating drug discovery approach in the past decades. Compared to single target-based drugs, combinati...

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Detalles Bibliográficos
Autores principales: Luo, Min, Jiao, Jianfeng, Wang, Ruiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509874/
https://www.ncbi.nlm.nih.gov/pubmed/31074386
http://dx.doi.org/10.1186/s12859-019-2730-8