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Screening drug target combinations in disease-related molecular networks
BACKGROUND: For treating a complex disease such as cancer, some effective means are needed to control biological networks that underlies the disease. The one-target one-drug paradigm has been the dominating drug discovery approach in the past decades. Compared to single target-based drugs, combinati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509874/ https://www.ncbi.nlm.nih.gov/pubmed/31074386 http://dx.doi.org/10.1186/s12859-019-2730-8 |