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A Cautionary Note on the Effects of Population Stratification Under an Extreme Phenotype Sampling Design
Extreme phenotype sampling (EPS) is a popular study design used to reduce genotyping or sequencing costs. Assuming continuous phenotype data are available on a large cohort, EPS involves genotyping or sequencing only those individuals with extreme phenotypic values. Although this design has been sho...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509877/ https://www.ncbi.nlm.nih.gov/pubmed/31130982 http://dx.doi.org/10.3389/fgene.2019.00398 |