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Melting Down Protein Stability: PAPS Synthase 2 in Patients and in a Cellular Environment

Within the crowded and complex environment of the cell, a protein experiences stabilizing excluded-volume effects and destabilizing quinary interactions with other proteins. Which of these prevail, needs to be determined on a case-by-case basis. PAPS synthases are dimeric and bifunctional enzymes, p...

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Detalles Bibliográficos
Autores principales: Brylski, Oliver, Ebbinghaus, Simon, Mueller, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509946/
https://www.ncbi.nlm.nih.gov/pubmed/31131283
http://dx.doi.org/10.3389/fmolb.2019.00031