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A single promoter system co-expressing RNA sensor with fluorescent proteins for quantitative mRNA imaging in living tumor cells

Genetically encoded light-up RNA aptamers afford a valuable platform for developing RNA sensors toward live cell imaging. However, quantitative imaging of intracellular RNAs remains a grand challenge. Here we reported a novel genetically encoded RNA sensor strategy using a plasmid that expresses a s...

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Detalles Bibliográficos
Autores principales: Ying, Zhan-Ming, Yuan, Yue-Yan, Tu, Bin, Tang, Li-Juan, Yu, Ru-Qin, Jiang, Jian-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509996/
https://www.ncbi.nlm.nih.gov/pubmed/31160957
http://dx.doi.org/10.1039/c9sc00458k