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Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle
Durable humoral immunity is dependent upon the generation of antigen-specific antibody titers, produced by non-proliferating bone marrow resident long-lived plasma cells (LLPC). Longevity is the hallmark of LLPC, but why and how they survive and function for years after antigen exposure is only begi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510054/ https://www.ncbi.nlm.nih.gov/pubmed/31130955 http://dx.doi.org/10.3389/fimmu.2019.00965 |