Understanding Ligand Binding to G-Protein Coupled Receptors Using Multiscale Simulations

Human G-protein coupled receptors (GPCRs) convey a wide variety of extracellular signals inside the cell and they are one of the main targets for pharmaceutical intervention. Rational drug design requires structural information on these receptors; however, the number of experimental structures is sc...

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Detalles Bibliográficos
Autores principales: Alfonso-Prieto, Mercedes, Navarini, Luciano, Carloni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510167/
https://www.ncbi.nlm.nih.gov/pubmed/31131282
http://dx.doi.org/10.3389/fmolb.2019.00029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510167/
https://www.ncbi.nlm.nih.gov/pubmed/31131282
http://dx.doi.org/10.3389/fmolb.2019.00029

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