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In silico analysis of suitable signal peptides for secretion of a recombinant alcohol dehydrogenase with a key role in atorvastatin enzymatic synthesis

An elevated cholesterol level might lead to cardiovascular disease (CVD). Statins block the cholesterol synthesis pathway in the liver. Atorvastatin is the most widespread statin worldwide and, its chemical synthesis requires toxic catalysts, resulting in environmental pollution. Hence, enzymatic sy...

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Detalles Bibliográficos
Autores principales: Taheri-Anganeh, Mortaza, Khatami, Seyyed Hossein, Jamali, Zeinab, Savardashtaki, Amir, Ghasemi, Younes, Mostafavi-Pour, Zohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510209/
https://www.ncbi.nlm.nih.gov/pubmed/31528640
http://dx.doi.org/10.22099/mbrc.2019.31801.1372