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In silico analysis of suitable signal peptides for secretion of a recombinant alcohol dehydrogenase with a key role in atorvastatin enzymatic synthesis
An elevated cholesterol level might lead to cardiovascular disease (CVD). Statins block the cholesterol synthesis pathway in the liver. Atorvastatin is the most widespread statin worldwide and, its chemical synthesis requires toxic catalysts, resulting in environmental pollution. Hence, enzymatic sy...
Autores principales: | Taheri-Anganeh, Mortaza, Khatami, Seyyed Hossein, Jamali, Zeinab, Savardashtaki, Amir, Ghasemi, Younes, Mostafavi-Pour, Zohreh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shiraz University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510209/ https://www.ncbi.nlm.nih.gov/pubmed/31528640 http://dx.doi.org/10.22099/mbrc.2019.31801.1372 |
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