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Genome mining and biosynthesis of kitacinnamycins as a STING activator

Cinnamoyl-containing nonribosomal peptides (CCNPs) are a small group of secondary metabolites with potent biological activities produced by actinobacteria. Two remarkable features in the biosynthesis of CCNPs include the nonribosomal peptide synthases (NRPSs) for assembly of the depsipeptide backbon...

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Detalles Bibliográficos
Autores principales: Shi, Jing, Liu, Cheng Li, Zhang, Bo, Guo, Wen Jie, Zhu, Jiapeng, Chang, Chin-Yuan, Zhao, Er Juan, Jiao, Rui Hua, Tan, Ren Xiang, Ge, Hui Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510318/
https://www.ncbi.nlm.nih.gov/pubmed/31160959
http://dx.doi.org/10.1039/c9sc00815b