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Comparison of Electrocardiographic Biomarkers for Differentiating Drug‐Induced Single vs. Multiple Cardiac Ion Channel Block

Since introduction of the International Conference on Harmonization proarrhythmia guidelines in 2005, no new marketed drugs have been associated with unacceptable risk of Torsade de Pointes. Although cardiac safety improved, these guidelines had the unintended consequence of eliminating potentially...

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Detalles Bibliográficos
Autores principales: Brockway, Marina, Mason, Jay W., Brockway, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510380/
https://www.ncbi.nlm.nih.gov/pubmed/30414356
http://dx.doi.org/10.1111/cts.12596