RAG2 localization and dynamics in the pre-B cell nucleus

RAG2 of the V(D)J recombinase is essential for lymphocyte development. Within the RAG2 noncore region is a plant homeodomain (PHD) that interacts with the modified histone H3K4me3, and this interaction is important for relieving inhibition of the RAG recombinase for V(D)J recombination. However, the...

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Detalles Bibliográficos
Autores principales: Rodgers, William, Byrum, Jennifer N., Simpson, Destiny A., Hoolehan, Walker, Rodgers, Karla K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510410/
https://www.ncbi.nlm.nih.gov/pubmed/31075127
http://dx.doi.org/10.1371/journal.pone.0216137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510410/
https://www.ncbi.nlm.nih.gov/pubmed/31075127
http://dx.doi.org/10.1371/journal.pone.0216137

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