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Different modes of barrel opening suggest a complex pathway of ligand binding in human gastrotropin
Gastrotropin, the intracellular carrier of bile salts in the small intestine, binds two ligand molecules simultaneously in its internal cavity. The molecular rearrangements required for ligand entry are not yet fully clear. To improve our understanding of the binding process we combined molecular dy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510414/ https://www.ncbi.nlm.nih.gov/pubmed/31075121 http://dx.doi.org/10.1371/journal.pone.0216142 |