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Genetic dissection of Escherichia coli's master diguanylate cyclase DgcE: Role of the N-terminal MASE1 domain and direct signal input from a GTPase partner system

The ubiquitous second messenger c-di-GMP promotes bacterial biofilm formation by playing diverse roles in the underlying regulatory networks. This is reflected in the multiplicity of diguanylate cyclases (DGC) and phosphodiesterases (PDE) that synthesize and degrade c-di-GMP, respectively, in most b...

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Detalles Bibliográficos
Autores principales: Pfiffer, Vanessa, Sarenko, Olga, Possling, Alexandra, Hengge, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510439/
https://www.ncbi.nlm.nih.gov/pubmed/31022167
http://dx.doi.org/10.1371/journal.pgen.1008059