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A multiscale model of epigenetic heterogeneity-driven cell fate decision-making

The inherent capacity of somatic cells to switch their phenotypic status in response to damage stimuli in vivo might have a pivotal role in ageing and cancer. However, how the entry-exit mechanisms of phenotype reprogramming are established remains poorly understood. In an attempt to elucidate such...

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Detalles Bibliográficos
Autores principales: Folguera-Blasco, Núria, Pérez-Carrasco, Rubén, Cuyàs, Elisabet, Menendez, Javier A., Alarcón, Tomás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510448/
https://www.ncbi.nlm.nih.gov/pubmed/31039148
http://dx.doi.org/10.1371/journal.pcbi.1006592