Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs

BACKGROUND: Shorter, more effective treatments for tuberculosis (TB) are urgently needed. While many TB drugs are available, identification of the best regimens is challenging because of the large number of possible drug-dose combinations. We have found consistently that responses of cells or whole...

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Detalles Bibliográficos
Autores principales: Clemens, Daniel L., Lee, Bai-Yu, Silva, Aleidy, Dillon, Barbara Jane, Masleša-Galić, Saša, Nava, Susana, Ding, Xianting, Ho, Chih-Ming, Horwitz, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510528/
https://www.ncbi.nlm.nih.gov/pubmed/31075149
http://dx.doi.org/10.1371/journal.pone.0215607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510528/
https://www.ncbi.nlm.nih.gov/pubmed/31075149
http://dx.doi.org/10.1371/journal.pone.0215607

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