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Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs
BACKGROUND: Shorter, more effective treatments for tuberculosis (TB) are urgently needed. While many TB drugs are available, identification of the best regimens is challenging because of the large number of possible drug-dose combinations. We have found consistently that responses of cells or whole...
Autores principales: | Clemens, Daniel L., Lee, Bai-Yu, Silva, Aleidy, Dillon, Barbara Jane, Masleša-Galić, Saša, Nava, Susana, Ding, Xianting, Ho, Chih-Ming, Horwitz, Marcus A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510528/ https://www.ncbi.nlm.nih.gov/pubmed/31075149 http://dx.doi.org/10.1371/journal.pone.0215607 |
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