Lithium chloride corrects weakness and myopathology in a preclinical model of LGMD1D

OBJECTIVE: To understand DNAJB6's function in skeletal muscle and identify therapeutic targets for limb-girdle muscular dystrophy 1D (LGMD1D). METHODS: DNAJB6 knockout (KO) myoblasts were generated with Crispr/cas9 technology, and differentially accumulated proteins were identified using stable...

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Detalles Bibliográficos
Autores principales: Findlay, Andrew R., Bengoechea, Rocio, Pittman, Sara K., Chou, Tsui-Fen, True, Heather L., Weihl, Conrad C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510529/
https://www.ncbi.nlm.nih.gov/pubmed/31123706
http://dx.doi.org/10.1212/NXG.0000000000000318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510529/
https://www.ncbi.nlm.nih.gov/pubmed/31123706
http://dx.doi.org/10.1212/NXG.0000000000000318

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