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Label-free quantitation of glycated hemoglobin in single red blood cells by transient absorption microscopy and phasor analysis

As a stable and accurate biomarker, glycated hemoglobin (HbA1c) is clinically used to diagnose diabetes with a threshold of 6.5% among total hemoglobin (Hb). Current methods such as boronate affinity chromatography involve complex processing of large-volume blood samples. Moreover, these methods can...

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Detalles Bibliográficos
Autores principales: Dong, Pu-Ting, Lin, Haonan, Huang, Kai-Chih, Cheng, Ji-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510558/
https://www.ncbi.nlm.nih.gov/pubmed/31093524
http://dx.doi.org/10.1126/sciadv.aav0561