A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signaling

Obesity is associated with an increased risk of depression. The aim of the present study was to investigate whether obesity is a causative factor for the development of depression and what is the molecular pathway(s) that link these two disorders. Using lipidomic and transcriptomic methods, we ident...

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Detalles Bibliográficos
Autores principales: Vagena, Eirini, Ryu, Jae Kyu, Baeza-Raja, Bernat, Walsh, Nicola M., Syme, Catriona, Day, Jonathan P., Houslay, Miles D., Baillie, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510753/
https://www.ncbi.nlm.nih.gov/pubmed/31076569
http://dx.doi.org/10.1038/s41398-019-0470-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510753/
https://www.ncbi.nlm.nih.gov/pubmed/31076569
http://dx.doi.org/10.1038/s41398-019-0470-1

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