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A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signaling
Obesity is associated with an increased risk of depression. The aim of the present study was to investigate whether obesity is a causative factor for the development of depression and what is the molecular pathway(s) that link these two disorders. Using lipidomic and transcriptomic methods, we ident...
Autores principales: | Vagena, Eirini, Ryu, Jae Kyu, Baeza-Raja, Bernat, Walsh, Nicola M., Syme, Catriona, Day, Jonathan P., Houslay, Miles D., Baillie, George S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510753/ https://www.ncbi.nlm.nih.gov/pubmed/31076569 http://dx.doi.org/10.1038/s41398-019-0470-1 |
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