Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury

Axonal degeneration occurs in various neurological diseases and traumatic nerve injury, and axonal regeneration is restricted by inhibitory factors in the central nervous system. Cyclin-dependent kinase 5 and glycogen synthase kinase 3β (GSK3β) are activated by one of those inhibitors, and collapsin...

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Detalles Bibliográficos
Autores principales: Kondo, Shunsuke, Takahashi, Kazuya, Kinoshita, Yuki, Nagai, Jun, Wakatsuki, Shuji, Araki, Toshiyuki, Goshima, Yoshio, Ohshima, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510754/
https://www.ncbi.nlm.nih.gov/pubmed/31076621
http://dx.doi.org/10.1038/s41598-019-43658-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510754/
https://www.ncbi.nlm.nih.gov/pubmed/31076621
http://dx.doi.org/10.1038/s41598-019-43658-w

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