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Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury
Axonal degeneration occurs in various neurological diseases and traumatic nerve injury, and axonal regeneration is restricted by inhibitory factors in the central nervous system. Cyclin-dependent kinase 5 and glycogen synthase kinase 3β (GSK3β) are activated by one of those inhibitors, and collapsin...
Autores principales: | Kondo, Shunsuke, Takahashi, Kazuya, Kinoshita, Yuki, Nagai, Jun, Wakatsuki, Shuji, Araki, Toshiyuki, Goshima, Yoshio, Ohshima, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510754/ https://www.ncbi.nlm.nih.gov/pubmed/31076621 http://dx.doi.org/10.1038/s41598-019-43658-w |
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