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PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection

The sensing of viral nucleic acids by the innate immune system activates a potent antiviral response in the infected cell, a key component of which is the expression of genes encoding type I interferons (IFNs). Many viruses counteract this response by blocking the activation of host nucleic acid sen...

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Detalles Bibliográficos
Autores principales: Rigby, Rachel E., Wise, Helen M., Smith, Nikki, Digard, Paul, Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510759/
https://www.ncbi.nlm.nih.gov/pubmed/31076606
http://dx.doi.org/10.1038/s41598-019-43632-6