Cargando…

Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in Western countries. It has recently been shown that the homogeneity of the chromatin landscape between CLL cells contrasts with the important observed genetic heterogeneity of the disease. To gain further insight into the consequence...

Descripción completa

Detalles Bibliográficos
Autores principales: Holmes, Katie B., Sadreev, Ildar I., Rawstron, Andy C., Munir, Tal, Westhead, David R., Hillmen, Peter, Lefevre, Pascal F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510766/
https://www.ncbi.nlm.nih.gov/pubmed/31076570
http://dx.doi.org/10.1038/s41389-019-0142-2