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A Systematic Review of the Clinical Efficacy and Safety of CFTR Modulators in Cystic Fibrosis

Several placebo-controlled trials have been recently published evaluating novel therapies targeting the defective CFTR protein. This systematic review examines the clinical efficacy and safety of CFTR modulators in individuals with cystic fibrosis (CF) with specific genetic mutations. Online sources...

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Detalles Bibliográficos
Autores principales: Habib, Al-Rahim R., Kajbafzadeh, Majid, Desai, Sameer, Yang, Connie L., Skolnik, Kate, Quon, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510767/
https://www.ncbi.nlm.nih.gov/pubmed/31076617
http://dx.doi.org/10.1038/s41598-019-43652-2