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A Systematic Review of the Clinical Efficacy and Safety of CFTR Modulators in Cystic Fibrosis
Several placebo-controlled trials have been recently published evaluating novel therapies targeting the defective CFTR protein. This systematic review examines the clinical efficacy and safety of CFTR modulators in individuals with cystic fibrosis (CF) with specific genetic mutations. Online sources...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510767/ https://www.ncbi.nlm.nih.gov/pubmed/31076617 http://dx.doi.org/10.1038/s41598-019-43652-2 |