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miR-494 induces EndMT and promotes the development of HCC (Hepatocellular Carcinoma) by targeting SIRT3/TGF-β/SMAD signaling pathway

EndMT has an important effect on metastasis and progression of tumor. This work will elucidate the effect of miR-494 on EndMT and development of HCC. Therefore, the differential miRNA expression among non-tumorous, para-tumorous and tumorous tissues was analyzed. Moreover, luciferase activities of S...

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Detalles Bibliográficos
Autores principales: Zhang, Jinqian, Zhu, Yan, Hu, Liangshan, Yan, Fang, Chen, Jinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510769/
https://www.ncbi.nlm.nih.gov/pubmed/31076630
http://dx.doi.org/10.1038/s41598-019-43731-4