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Molecular mechanisms underlying uremic toxin-related systemic disorders in chronic kidney disease: focused on β(2)-microglobulin-related amyloidosis and indoxyl sulfate-induced atherosclerosis—Oshima Award Address 2016

Uremic toxins are linked to chronic kidney disease (CKD)-related systemic diseases. β(2)-Microglobulin (β(2)-m), a water-soluble, middle-sized molecule, is associated with mortality and dialysis-related amyloidosis (DRA). DRA occurs in long-term dialysis patients, with β(2)-m amyloid deposited mainl...

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Detalles Bibliográficos
Autor principal: Yamamoto, Suguru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510801/
https://www.ncbi.nlm.nih.gov/pubmed/29869756
http://dx.doi.org/10.1007/s10157-018-1588-9