Cargando…

Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice

A potential therapeutic strategy for diabetes is the transplantation of induced-insulin secreting cells. Based on the common embryonic origin of liver and pancreas, we studied the potential of adult human liver stem-like cells (HLSC) to generate in vitro insulin-producing 3D spheroid structures (HLS...

Descripción completa

Detalles Bibliográficos
Autores principales: Navarro-Tableros, Victor, Gai, Chiara, Gomez, Yonathan, Giunti, Sara, Pasquino, Chiara, Deregibus, Maria Chiara, Tapparo, Marta, Pitino, Adriana, Tetta, Ciro, Brizzi, Maria Felice, Ricordi, Camillo, Camussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510809/
https://www.ncbi.nlm.nih.gov/pubmed/30191384
http://dx.doi.org/10.1007/s12015-018-9845-6