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Islet-Like Structures Generated In Vitro from Adult Human Liver Stem Cells Revert Hyperglycemia in Diabetic SCID Mice
A potential therapeutic strategy for diabetes is the transplantation of induced-insulin secreting cells. Based on the common embryonic origin of liver and pancreas, we studied the potential of adult human liver stem-like cells (HLSC) to generate in vitro insulin-producing 3D spheroid structures (HLS...
Autores principales: | Navarro-Tableros, Victor, Gai, Chiara, Gomez, Yonathan, Giunti, Sara, Pasquino, Chiara, Deregibus, Maria Chiara, Tapparo, Marta, Pitino, Adriana, Tetta, Ciro, Brizzi, Maria Felice, Ricordi, Camillo, Camussi, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510809/ https://www.ncbi.nlm.nih.gov/pubmed/30191384 http://dx.doi.org/10.1007/s12015-018-9845-6 |
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