Identification of anticancer OATP2B1 substrates by an in vitro triple-fluorescence-based cytotoxicity screen

Membrane transporters play an important role in the absorption, distribution, metabolism and excretion of drugs. The cellular accumulation of many drugs is the result of the net function of efflux and influx transporters. Efflux transporters such as P-glycoprotein/ABCB1 have been shown to confer mul...

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Detalles Bibliográficos
Autores principales: Windt, Tímea, Tóth, Szilárd, Patik, Izabel, Sessler, Judit, Kucsma, Nóra, Szepesi, Áron, Zdrazil, Barbara, Özvegy-Laczka, Csilla, Szakács, Gergely
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
In Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510822/
https://www.ncbi.nlm.nih.gov/pubmed/30863990
http://dx.doi.org/10.1007/s00204-019-02417-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510822/
https://www.ncbi.nlm.nih.gov/pubmed/30863990
http://dx.doi.org/10.1007/s00204-019-02417-6

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