Versatility of the Mec1(ATM/ATR) signaling network in mediating resistance to replication, genotoxic, and proteotoxic stresses

The ataxia-telangiectasia mutated/ATM and Rad3-related (ATM/ATR) family proteins are evolutionarily conserved serine/threonine kinases best known for their roles in mediating the DNA damage response. Upon activation, ATM/ATR phosphorylate numerous targets to stabilize stalled replication forks, repa...

Descripción completa

Detalles Bibliográficos
Autores principales: Corcoles-Saez, Isaac, Dong, Kangzhen, Cha, Rita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510830/
https://www.ncbi.nlm.nih.gov/pubmed/30610294
http://dx.doi.org/10.1007/s00294-018-0920-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510830/
https://www.ncbi.nlm.nih.gov/pubmed/30610294
http://dx.doi.org/10.1007/s00294-018-0920-y

Ejemplares similares