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Versatility of the Mec1(ATM/ATR) signaling network in mediating resistance to replication, genotoxic, and proteotoxic stresses

The ataxia-telangiectasia mutated/ATM and Rad3-related (ATM/ATR) family proteins are evolutionarily conserved serine/threonine kinases best known for their roles in mediating the DNA damage response. Upon activation, ATM/ATR phosphorylate numerous targets to stabilize stalled replication forks, repa...

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Detalles Bibliográficos
Autores principales:	Corcoles-Saez, Isaac, Dong, Kangzhen, Cha, Rita S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Mini-Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510830/ https://www.ncbi.nlm.nih.gov/pubmed/30610294 http://dx.doi.org/10.1007/s00294-018-0920-y

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