Hemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species

Proteasome inhibition represents an important anticancer strategy. Here, we studied the mechanisms at the basis of the pro-apoptotic activity of the standardized decoction of Hemidesmus indicus, a plant evoking a complex anticancer activity, and explored its inhibition of proteasome activity in huma...

Descripción completa

Detalles Bibliográficos
Autores principales: Turrini, Eleonora, Catanzaro, Elena, Ferruzzi, Lorenzo, Guerrini, Alessandra, Tacchini, Massimo, Sacchetti, Gianni, Paganetto, Guglielmo, Maffei, Francesca, Pellicioni, Valentina, Poli, Ferruccio, Hrelia, Patrizia, Mandrone, Manuela, Sestili, Piero, Brigotti, Maurizio, Fimognari, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510901/
https://www.ncbi.nlm.nih.gov/pubmed/31076590
http://dx.doi.org/10.1038/s41598-019-43609-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510901/
https://www.ncbi.nlm.nih.gov/pubmed/31076590
http://dx.doi.org/10.1038/s41598-019-43609-5

Ejemplares similares