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Unifying photocycle model for light adaptation and temporal evolution of cation conductance in channelrhodopsin-2

Although channelrhodopsin (ChR) is a widely applied light-activated ion channel, important properties such as light adaptation, photocurrent inactivation, and alteration of the ion selectivity during continuous illumination are not well understood from a molecular perspective. Herein, we address the...

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Detalles Bibliográficos
Autores principales: Kuhne, Jens, Vierock, Johannes, Tennigkeit, Stefan Alexander, Dreier, Max-Aylmer, Wietek, Jonas, Petersen, Dennis, Gavriljuk, Konstantin, El-Mashtoly, Samir F., Hegemann, Peter, Gerwert, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510988/
https://www.ncbi.nlm.nih.gov/pubmed/31004059
http://dx.doi.org/10.1073/pnas.1818707116